Will Sam and Dante Reunite on General Hospital? Dominic Zamprogna Shares His Thoughts

Kelly Monaco’s exit from General Hospital marks the end of an era for fans of the long-running soap opera. For over 21 years, Monaco portrayed Sam McCall, a character who became one of the show's most iconic figures. Her departure is bittersweet, and while it may be the end of her character’s journey on GH, the memories of her portrayal are sure to live on with viewers.

Monaco’s time on General Hospital began back in 2003 when she first appeared as Sam McCall, a role that cemented her as a fan favorite. Prior to GH, she played Livvie Locke on the Port Charles spinoff, and her soap experience had already made her a familiar face in the daytime drama world. Over the years, Monaco’s performance earned her widespread acclaim, including Daytime Emmy nominations, a testament to the depth and nuance she brought to her role.

In August, news broke that Monaco had been "blindsided" by GH’s decision to kill off her character, Sam McCall. This was especially surprising given her long tenure on the show. Fans were already grappling with the bittersweet storyline leading up to Sam’s death. After agreeing to donate her liver to Lulu Spencer, Sam underwent surgery in October, which viewers initially hoped would be a turning point for the character.

In a twist of fate, after the surgery was successful, Sam even got engaged to her longtime love interest, Dante Falconeri (Dominic Zamprogna), celebrating what appeared to be a happy ending. Unfortunately, the celebration was short-lived, as Sam’s condition worsened, and she tragically passed away shortly after.

Dominic Zamprogna, who played Sam’s on-screen love interest, Dante, had the honor of filming her final scenes. Reflecting on the experience, Zamprogna shared heartfelt praise for Monaco’s professionalism, especially considering the circumstances of her departure. Speaking with Soap Opera Digest, he remarked, “In her final weeks of filming — and despite leaving the soap under clearly not happy circumstances — Monaco was amazing. Amazing, amazing, amazing.”

The emotional weight of their final scenes together is evident, as Zamprogna recalled how his monologues were Sam’s last moments on the show. “I basically said good-bye to Kelly then and there,” he shared, a testament to the personal connection they had built over years of working together.

Even after Monaco’s exit, Zamprogna continues to check in on her weekly, showing that the bond formed through their years on General Hospital goes far beyond the screen. "I still check in on her every week," he said. "I would not be surprised if we somehow, somewhere, end up sharing GH scenes again. It’s a soap. Who the heck knows what’s gonna happen?"

That sentiment speaks to the unpredictable nature of soap operas. After all, the world of daytime drama is filled with twists and turns, and with the constant ebb and flow of storylines, anything is possible. In the world of General Hospital, where characters often return from the dead or are revealed to have been living undercover for years, it’s not beyond the realm of possibility for Sam McCall to somehow resurface—whether in flashbacks, dreams, or a storyline twist.

For General Hospital fans, Kelly Monaco’s portrayal of Sam McCall will remain one of the defining characters of the show. From her tough exterior to her vulnerable moments, Sam has been involved in some of the most memorable storylines over the years, including complex love triangles, thrilling action-packed sequences, and moments of deep emotional turmoil. Her journey from being a private investigator and con artist to becoming a mother and a beloved figure in the town of Port Charles left a lasting impact on fans.

Monaco’s character arc and her performances have earned her a devoted following, and while Sam may no longer be a part of General Hospital, Monaco’s legacy in the soap opera world will remain untarnished. Whether or not she returns to Port Charles in the future, it’s clear that the end of her run on the show marks the close of an unforgettable chapter in daytime drama history.

As Zamprogna wisely put it, "Who the heck knows what’s gonna happen?" So, while fans say goodbye to Sam for now, they hold on to the hope that, in the unpredictable world of soaps, anything is possible.